A laser microdissection system includes a microscope that includes a reflected light device having a laser deflector which guides a laser beam provided by a laser through a microscope objective of the microscope onto a sample region for receiving a biological sample and which moves a point of impingement of the laser beam in the sample region. The laser microdissection system also includes a rinsing device comprising fluid dispenser configured to provide a suspension fluid in the sample region and a fluid remover arranged on the rinsing device configured to remove a suspension produced using the suspension fluid from the sample region.