发明申请
US20160256604A1 TUNABLE COVALENTLY CROSSLINKED HYDROGELS AND METHODS OF MAKING THE SAME
审中-公开
可连接的交联氢化物及其制备方法
- 专利标题: TUNABLE COVALENTLY CROSSLINKED HYDROGELS AND METHODS OF MAKING THE SAME
- 专利标题(中): 可连接的交联氢化物及其制备方法
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申请号: US15027468申请日: 2014-10-06
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公开(公告)号: US20160256604A1公开(公告)日: 2016-09-08
- 发明人: Craig W. Hanna , Benjamin P. Partlow , David L. Kaplan
- 申请人: TRUSTEES OF TUFTS COLLEGE
- 国际申请: PCT/US2014/059287 WO 20141006
- 主分类号: A61L27/22
- IPC分类号: A61L27/22 ; C12P21/00 ; A61L27/50 ; A61L27/54 ; A61L27/52 ; A61L27/38
摘要:
The present invention provides, among other things, a elastomeric biomaterial having enzymatically cross-linked amino acid phenolic side chains to generate highly elastic hydrogels. Materials are characterized by tunable mechanical properties, gelation kinetics and swelling properties of these new protein polymers. Provided materials are support encapsulation of cells. Methods of making and using of provided particles are also disclosed.
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