Embodiments of the inventive concept include 2.5 inch hard disk drive form factor solid state drive multi-card adapters that can include multiple M.2 solid state drive cards, which can be incorporated into existing enterprise servers without major architectural changes, thereby enabling the server industry ecosystem to easily integrate M.2 solid state drive technology into servers. Multiple M.2 solid state drive cards and a peripheral component interconnect express (PCIe) switch can be included within a 2.5 inch hard disk drive form factor solid state drive multi-card adapter. The solid state drive multi-card adapters can be attached to or seated within drive bays of a computer server that supports non-volatile memory express (NVMe) 2.5 inch drives without any changes to the server architecture, thereby providing a straight-forward upgrade path.