发明申请
- 专利标题： USE OF MEGANUCELASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
- 专利标题（中）： 用于诱导异体重组的血管内皮生长因子及其在皮肤组织中的应用
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申请号： US15080232申请日： 2016-03-24
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公开(公告)号： US20160273003A1公开(公告)日： 2016-09-22
- 发明人: Philippe DUCHATEAU , Christophe PEREZ , Sylvia BRUNEAU , Jean-Pierre CABANIOLS , Julianne SMITH , Agnes GOUBLE
- 申请人： Cellectis S.A.
- 主分类号： C12N15/90
- IPC分类号： C12N15/90 ; C07K14/435 ; C12N15/86 ; C12N9/22 ; A61K38/46 ; C12N7/00
摘要：
A single chain homing endonuclease, comprising a first variant of I-CreI having the amino acid sequence of accession number pdb 1g9y and a second variant of I-CreI variant having the amino acid sequence of accession number pdb 1g9y in a single polypeptide.
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IPC分类:
