Invention Application
- Patent Title: USE OF MEGANUCELASES FOR INDUCING HOMOLOGOUS RECOMBINATION EX VIVO AND IN TOTO IN VERTEBRATE SOMATIC TISSUES AND APPLICATION THEREOF
- Patent Title (中): 用于诱导异体重组的血管内皮生长因子及其在皮肤组织中的应用
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Application No.: US15080232Application Date: 2016-03-24
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Publication No.: US20160273003A1Publication Date: 2016-09-22
- Inventor: Philippe DUCHATEAU , Christophe PEREZ , Sylvia BRUNEAU , Jean-Pierre CABANIOLS , Julianne SMITH , Agnes GOUBLE
- Applicant: Cellectis S.A.
- Main IPC: C12N15/90
- IPC: C12N15/90 ; C07K14/435 ; C12N15/86 ; C12N9/22 ; A61K38/46 ; C12N7/00
Abstract:
A single chain homing endonuclease, comprising a first variant of I-CreI having the amino acid sequence of accession number pdb 1g9y and a second variant of I-CreI variant having the amino acid sequence of accession number pdb 1g9y in a single polypeptide.
Information query
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