发明申请
- 专利标题： Triazolopyridine Derivatives As Modulators of TNF Activity
- 专利标题（中）： 作为TNF活性调节剂的三唑并吡啶衍生物
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申请号： US15101044申请日： 2014-12-08
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公开(公告)号： US20160304512A1公开(公告)日： 2016-10-20
- 发明人: Daniel Christopher Brookings , Victoria Elizabeth Jackson
- 申请人： UCB BIOPHARMA SPRL
- 优先权： GB1321742.7 20131209
- 国际申请： PCT/EP2014/076832 WO 20141208
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/506 ; A61K31/437 ; A61K31/5377
摘要：
A series of substituted [1,2,4]triazolo[4,3-a]pyridine derivatives, being potent modulators of human TNF activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
公开/授权文献
- US09850240B2 Triazolopyridine derivatives as modulators of TNF activity 公开/授权日：2017-12-26
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