Invention Application
US20160347866A1 NOVEL ESTERIFIED CELLULOSE ETHERS OF HIGH MOLECULAR WEIGHT AND HOMOGENEITY
审中-公开
高分子量和均匀性的新型细胞纤维素
- Patent Title: NOVEL ESTERIFIED CELLULOSE ETHERS OF HIGH MOLECULAR WEIGHT AND HOMOGENEITY
- Patent Title (中): 高分子量和均匀性的新型细胞纤维素
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Application No.: US15113921Application Date: 2015-01-27
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Publication No.: US20160347866A1Publication Date: 2016-12-01
- Inventor: Oliver Petermann , Matthias Sprehe , Meinolf Brackhagen
- Applicant: DOW GLOBAL TECHNOLOGIES LLC
- Applicant Address: US MI Midland
- Assignee: Dow Global Technologies LLC
- Current Assignee: Dow Global Technologies LLC
- Current Assignee Address: US MI Midland
- International Application: PCT/US2015/012981 WO 20150127
- Main IPC: C08B13/00
- IPC: C08B13/00 ; A61K9/10 ; A61K9/48 ; A61K47/38

Abstract:
Esterified cellulose ethers which have i) as ester groups aliphatic monovalent acyl groups or a combination of aliphatic monovalent acyl groups and groups of the formula ——C(O)—R—COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, ii) a weight average molecular weight Mw of from 80,000 Dalton to 220,000 Dalton, iii) a Polydispersity Mw/Mn of from 1.3 to 4.0, and iv) an Mz/Mn of not more than 18.5, when the weight average molecular weight Mw, the number average molecular weight Mn and the z-average molecular weight Mz are measured by SEC-MALLS using as mobile phase a mixture produced from 40 parts by volume of acetonitrile and 60 parts by volume of aqueous buffer containing 50 mM NaH2—PO4 and 0.1 M NaNO3. are useful as enteric polymers for pharmaceutical dosage forms.
Public/Granted literature
- US10759873B2 Esterified cellulose ethers of high molecular weight and homogeneity Public/Granted day:2020-09-01
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