A method for the quantitative characterization of amyloid and/or aggregated peptides and/or proteins in a sample, comprising: providing a sample, wherein the sample includes an amyloid and/or aggregated peptide and/or protein having at least one aggregate size and shape; adding an active ingredient to be analyzed to the sample solution; separating the amyloid and/or aggregated peptides and/or proteins are from one another according to their aggregate size and shape; optionally completely denaturing the amyloid and/or aggregated peptides and/or proteins of a particular fraction into monomer building blocks; determining the change in concentration of the peptide and/or protein building blocks in at least one fraction by comparison against control values without the active ingredient.