发明申请
- 专利标题： COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER
- 专利标题（中）： 用于治疗癌症的组合物和方法
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申请号： US15241240申请日： 2016-08-19
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公开(公告)号： US20160355515A1公开(公告)日： 2016-12-08
- 发明人: Chiang J. Li , Mark A. Ashwell , Jason Hill , Magdi Moussa , Neru Munshi
- 申请人： ArQule, Inc.
- 主分类号： C07D471/06
- IPC分类号： C07D471/06 ; A61K31/5377 ; A61K31/5517 ; A61K31/683 ; C07D487/06 ; A61K31/4745 ; C07F9/6561
摘要：
The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent.
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