发明申请
- 专利标题： METHOD FOR THE ENZYMATIC PRODUCTION OF 3-BUTEN-2-ONE
- 专利标题（中）： 3- BUTEN-2-ONE的生产方法
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申请号： US14902565申请日： 2014-07-02
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公开(公告)号： US20160369306A1公开(公告)日： 2016-12-22
- 发明人: Philippe Marliere , Maria Anissimova , Mathieu Allard
- 申请人： SCIENTIST OF FORTUNE S.A. , GLOBAL BIOENERGIES
- 优先权： EP13174973.1 20130703
- 国际申请： PCT/EP2014/064102 WO 20140702
- 主分类号： C12P7/16
- IPC分类号： C12P7/16 ; C12N9/88 ; C12N15/52 ; C12N15/70 ; C12P7/26 ; C12P19/32 ; C12N9/02 ; C12N9/04 ; C12P5/02
摘要：
Described is a method for the production of 3-buten-2-one comprising the enzymatic conversion of 4-hydroxy-2-butanone into 3-buten-2-one by making use of an enzyme catalyzing 4-hydroxy-2-butanone dehydration, wherein said enzyme catalyzing 4-hydroxy-2-butanone dehydration is (a) a 3-hydroxypropiony-CoA dehydratase (EC 4.2.1.116), (b) a 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55), (c) an enoyl-CoA hydratase (EC 4.2.1.17), (d) a 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59), (e) a crotonyl-[acyl-carrier-protein] hydratase (EC 4.2.1.58), (f) a 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60), (g) a 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61), (h) a long-chain-enoyl-CoA hydratase (EC 4.2.1.74), or (i) a 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18). The produced 3-buten-2-one can be further converted into 3-buten-2-ol and finally into 1,3-butadiene.
公开/授权文献
- US09850504B2 Method for the enzymatic production of 3-buten-2-one 公开/授权日：2017-12-26
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