Invention Application
- Patent Title: Solid Pharmaceutical Compositions for Treating HCV
- Patent Title (中): 用于治疗HCV的固体药物组合物
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Application No.: US15212997Application Date: 2016-07-18
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Publication No.: US20160375017A1Publication Date: 2016-12-29
- Inventor: Katharina Asmus , Yi Gao , Colleen Garrett , Harald Hach , Adivaraha Jayasankar , Kyeremateng Samuel , Ute Lander , Thomas Mueller , Marius Naris , Constanze Obermiller , Regina Reul , Katrin Schneider , Nancy Sever , Michael Simon , Benedikt Steitz , Ping Tong , Ulrich Westedt , Donghua Zhu
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: A61K31/498
- IPC: A61K31/498 ; A61K9/20 ; A61K9/24 ; A61K31/454 ; A61K9/10

Abstract:
The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
Information query
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