Invention Application
- Patent Title: Solid Pharmaceutical Compositions for Treating HCV
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Application No.: US15192211Application Date: 2016-06-24
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Publication No.: US20160375087A1Publication Date: 2016-12-29
- Inventor: Nancy E. Sever , Ulrich Westedt , Ute Lander , Katrin Schneider , Benedikt Steitz , Thomas Mueller , Regina Reul , Constanze Obermiller , Adivaraha Jayasankar , Michael Simon , Yi Gao , Harald Hach , Samuel Kyeremateng , Katharina Asmus , Ping Tong , Donghua Zhu , Marius Naris , Colleen Garrett
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: A61K38/06
- IPC: A61K38/06 ; A61K9/28 ; A61K9/20 ; A61K9/16 ; A61K31/4184 ; A61K9/24

Abstract:
The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
Information query
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