发明申请
- 专利标题： FUNCTIONALLY-MODIFIED OLIGONUCLEOTIDES AND SUBUNITS THEREOF
- 专利标题（中）： 功能改性的寡核苷酸及其亚基
-
申请号： US15007017申请日： 2016-01-26
-
公开(公告)号： US20160376587A1公开(公告)日： 2016-12-29
- 发明人: Gunnar J. Hanson , Dwight D. Weller , Bao Zhong Cai , Ming Zhou
- 申请人： Sarepta Therapeutics, Inc.
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
公开/授权文献
- US09790499B2 Functionally-modified oligonucleotides and subunits thereof 公开/授权日：2017-10-17
信息查询
IPC分类:
