Embodiments of the present invention provide a power control method and a device. The power control method provided includes: estimating, by a BS, receiving quality of an uplink channel transmitted by UE, and generating an uplink TPC command, where the UE is configured in a compressed mode, and configuration information in the compressed mode includes a transmission interval and a non-transmission interval; and increasing a current transmit power of the uplink TPC command according to the configuration information of the UE in the compressed mode, and repeatedly transmitting the uplink TPC command to the UE. In the embodiments of the present invention, power control accuracy is increased.