Invention Application
- Patent Title: POLYMORPHIC FORMS AND CO-CRYSTALS OF A C-MET INHIBITOR
- Patent Title (中): C-MET抑制剂的多晶形态和共晶体
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Application No.: US15293511Application Date: 2016-10-14
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Publication No.: US20170029443A1Publication Date: 2017-02-02
- Inventor: David BAUER , Matthew BIO , Melanie COOKE , Katrina W. COPELAND , Matthew PETERSON , Michele POTASHMAN , Roman SHIMANOVICH , Helming TAN
- Applicant: AMGEN, INC.
- Main IPC: C07D519/00
- IPC: C07D519/00 ; C07C275/02 ; C07C57/10 ; C07C55/12 ; C07C57/145 ; C07C55/10

Abstract:
Provided herein are novel polymorphic forms and co-crystals of a compound useful in the treatment, prevention, or amelioration of cancer. In particular, the invention provides polymorphs and co-crystals of 6-{(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, which is an inhibitor of c-Met.
Public/Granted literature
- US09981988B2 Polymorphic forms and co-crystals of a c-Met inhibitor Public/Granted day:2018-05-29
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