Systems, methods, and computer readable medium are provided that improve the management of interrupt requests in multiple processor computer systems. Interrupt requests can be classified into three categories and the structure of the categories provide for specifying a list that needs to be migrated. The list can contain only those interrupt requests that can be handled by some of the processors that will never unplug or based on affinity. When a processor is about to unplug, the computer system can migrate that list. The system can also manage the other interrupt requests.