Invention Application
US20170044174A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS
审中-公开
杂环化合物及其作为多巴胺D1配体使用
- Patent Title: HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS
- Patent Title (中): 杂环化合物及其作为多巴胺D1配体使用
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Application No.: US15305384Application Date: 2015-04-14
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Publication No.: US20170044174A1Publication Date: 2017-02-16
- Inventor: DAVID LAWRENCE FIRMAN GRAY , LEI ZHANG , MICHAEL AARON BRODNEY , JENNIFER ELIZABETH DAVOREN , IVAN VIKTOROVICH EFREMOV , MICHAEL ERIC GREEN , STEVEN VICTOR O'NEIL , BRUCE NELSEN ROGERS
- Applicant: PFIZER INC.
- Applicant Address: US NY NEW YORK
- Assignee: PFIZER INC.
- Current Assignee: PFIZER INC.
- Current Assignee Address: US NY NEW YORK
- International Application: PCT/IB2015/052715 WO 20150414
- Main IPC: C07D491/048
- IPC: C07D491/048 ; C07D403/12 ; C07D491/052 ; C07D471/04 ; C07D487/04

Abstract:
The present invention provides, in part, compounds of Formula (I): and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.
Public/Granted literature
- US09745317B2 Heterocyclic compounds and their use as dopamine D1 ligands Public/Granted day:2017-08-29
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