Invention Application
US20170044516A1 BIOCHEMISTRY REACTIVE MATERIAL AND DEVICE FOR ELIMINATING ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN (LDL) AND METHOD FOR TREATING BLOOD OR PLASMA EX VIVO TO ELIMINATE ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN THEREIN
审中-公开
用于消除电子低密度脂蛋白（LDL）的生物化学反应性材料和装置以及用于治疗血液或血浆的方法以消除电子密度低密度脂蛋白
- Patent Title: BIOCHEMISTRY REACTIVE MATERIAL AND DEVICE FOR ELIMINATING ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN (LDL) AND METHOD FOR TREATING BLOOD OR PLASMA EX VIVO TO ELIMINATE ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN THEREIN
- Patent Title (中): 用于消除电子低密度脂蛋白（LDL）的生物化学反应性材料和装置以及用于治疗血液或血浆的方法以消除电子密度低密度脂蛋白
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Application No.: US14984938Application Date: 2015-12-30
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Publication No.: US20170044516A1Publication Date: 2017-02-16
- Inventor: Pei-Yi Tsai , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
- Applicant: Industrial Technology Research Institute
- Applicant Address: TW Hsinchu
- Assignee: Industrial Technology Research Institute
- Current Assignee: Industrial Technology Research Institute
- Current Assignee Address: TW Hsinchu
- Priority: TW104126050 20150811; CN201510815421.4 20151123
- Main IPC: C12N11/12
- IPC: C12N11/12 ; A61M1/34 ; C12M1/00
Abstract:
The present disclosure provides a biochemistry reactive material, including a substrate and an enzyme composition immobilized on the substrate. The enzyme composition is selected from a group consisting of a first enzyme, a second enzyme, and a combination thereof. The first enzyme is used for eliminating a glycan residue of an electronegative low-density lipoprotein (electronegative LDL). The second enzyme is used for eliminating ceramide carried by an electronegative low-density lipoprotein. The biochemistry reactive material is capable of eliminating electronegative low-density lipoprotein.
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