发明申请
US20170057896A1 Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions
有权
在纤维化和糖尿病状态治疗中使用二氢白藜芦醇或其芪衍生物和/或化学变体的方法
- 专利标题： Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions
- 专利标题（中）： 在纤维化和糖尿病状态治疗中使用二氢白藜芦醇或其芪衍生物和/或化学变体的方法
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申请号： US15351636申请日： 2016-11-15
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公开(公告)号： US20170057896A1公开(公告)日： 2017-03-02
- 发明人: Hongjie ZHANG , Siu Wai TSANG , Yegao CHEN
- 申请人： Hong Kong Baptist University
- 专利权人： Hong Kong Baptist University
- 当前专利权人： Hong Kong Baptist University
- 主分类号： C07C43/23
- IPC分类号： C07C43/23 ; C07C39/16
摘要：
A polyphenol derivative of the stilbenoid family, namely trans-3,5,4′-trihydroxybibenzyl, also known as dihydro-resveratrol, is disclosed as a remedial agent. In particular, the usage of dihydro-resveratrol as an anti-fibrotic agent in suppressing the activation of pancreatic stellate cells (PSCs) is presented. One embodiment also relates to the management of pancreatic fibrosis, which is often accompanied with chronic pancreatitis and desmoplastic reaction of pancreatic cancer. Another embodiment has applications in preventing or alleviating or treating pancreatic cancer or pancreatogenic diabetes.
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