发明申请
US20170066795A1 SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV
审中-公开
用于HCV的2'-氯-2'-甲基脲的固体制剂
- 专利标题: SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV
- 专利标题(中): 用于HCV的2'-氯-2'-甲基脲的固体制剂
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申请号: US15123124申请日: 2015-03-05
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公开(公告)号: US20170066795A1公开(公告)日: 2017-03-09
- 发明人: John Zoltan Sulliva-Bolyai , Benjamin Alexander Mayes , Douglas Lytle Mayers , Xiao-Jian Zhou , Adel M. Moussa , Alistair James Stewart , Sindhura Ganga , Clinton Scott Shultz , Alfred Lee
- 申请人: IDENIX PHARMACEUTICALS LLC , Merck Sharp & Dohme Corp.
- 申请人地址: US MA Cambridge US NJ Rahway
- 专利权人: IDENIX PHARMACEUTICALS LLC,Merck Sharp & Dohme Corp.
- 当前专利权人: IDENIX PHARMACEUTICALS LLC,Merck Sharp & Dohme Corp.
- 当前专利权人地址: US MA Cambridge US NJ Rahway
- 国际申请: PCT/US2015/019021 WO 20150305
- 主分类号: C07H19/10
- IPC分类号: C07H19/10 ; A61K9/48 ; A61K31/7072 ; A61K9/20
摘要:
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are solid forms of Compound I: (Compound I)
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