- 专利标题： IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF
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申请号： US15341870申请日： 2016-11-02
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公开(公告)号： US20170114140A1公开(公告)日： 2017-04-27
- 发明人: Alison L. Budelsky , Michael R. Comeau , Joel E. Tocker
- 申请人： KIRIN-AMGEN, INC.
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as various methods of use.
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