- 专利标题: SELF-ASSEMBLING NANOPARTICLE DRUG DELIVERY SYSTEM
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申请号: US15183167申请日: 2016-06-15
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公开(公告)号: US20170119689A1公开(公告)日: 2017-05-04
- 发明人: Miguel A. de los Rios , Kenneth J. Oh
- 申请人: Miguel A. de los Rios , Kenneth J. Oh
- 主分类号: A61K9/51
- IPC分类号: A61K9/51 ; A61K9/127 ; C12N7/00
摘要:
A self-assembling nanoparticle drug delivery system for the delivery of drugs including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as Hepatitis B Virus core protein, encapsulating the drug, a lipid bi-layer envelope and targeting or facilitating molecules anchored in the lipid bilayer. A method for construction of the self-assembling nanoparticle drug delivery system is also provided.