- 专利标题： METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA)
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申请号： US15366877申请日： 2016-12-01
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公开(公告)号： US20170151250A1公开(公告)日： 2017-06-01
- 发明人: Stanley Leon HAZEN , Jose Carlos GARCIA-GARCIA , George Franklin GERBERICK , John August WOS , David Thomas STANTON , Thomas Alfred INGLIN , Michael REILLY , Angela Jane DEUTSCH , Jodie Michele REED , David Blair CODY
- 申请人： The Procter & Gamble Company
- 主分类号： A61K31/5375
- IPC分类号： A61K31/5375 ; A61K31/166 ; A61K31/351 ; A61K31/216 ; A61K31/22 ; A61K31/145 ; A61K31/325
摘要：
The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I): Wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual.
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