- 专利标题： Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
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申请号： US15449565申请日： 2017-03-03
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公开(公告)号： US20170173009A1公开(公告)日： 2017-06-22
- 发明人: Wilhelm Amberg , Frauke Pohlki , Udo Lange , Ying Wang , Jason Brewer , Anil Vasudevan , Yanbin Lao , Charles Hutchins , Hongyu Zhao , Huan-Qiu Li
- 申请人： AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- 主分类号： A61K31/501
- IPC分类号： A61K31/501 ; A61K31/4433 ; A61K31/4155 ; A61K31/4192 ; A61K31/4178 ; A61K31/397
摘要：
The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquin oline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.
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