- 专利标题: BENZOTHIAZOLE COMPOUND AND MEDICINE CONTAINING SAME
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申请号: US15326320申请日: 2015-07-15
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公开(公告)号: US20170197956A1公开(公告)日: 2017-07-13
- 发明人: Motomu KANAI , Yohei SOMA , Atsuhiko TANIGUCHI , Yusuke SHIMIZU
- 申请人: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- 申请人地址: JP Kawaguchi-shi
- 专利权人: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- 当前专利权人: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- 当前专利权人地址: JP Kawaguchi-shi
- 优先权: JP2014-145736 20140716
- 国际申请: PCT/JP2015/070317 WO 20150715
- 主分类号: C07D455/04
- IPC分类号: C07D455/04 ; C07D417/04
摘要:
It is intended to provide: a compound useful as an amyloid oxidation catalyst which is applicable in vivo and is applicable not only to Aβ peptides but to other amyloids; and a prophylactic or therapeutic drug for an amyloid-related disease, comprising the same. The present invention provides a benzothiazole compound represented by the following formula (1) wherein X represents a halogen atom; R1 represents an optionally substituted hydrocarbon group; R2 represents a hydrogen atom or an optionally substituted hydrocarbon group; R3 and R4 are the same or different and each represent a hydrogen atom, an optionally substituted hydrocarbon group, an alkoxy group, a halogen atom, an amino group, a nitro group, or a cyano group; R2 and R4 optionally together form an alkylene group; and R5 represents an anion.
公开/授权文献
- US09932333B2 Benzothiazole compound and medicine containing same 公开/授权日:2018-04-03
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