For example, a wireless station may be configured to modulate a plurality of data bit sequences into a plurality of data blocks in a frequency domain according to a dual carrier modulation, a data bit sequence of the plurality of data bit sequences to be modulated into first and second consecutive symbols in a data block of the plurality of data blocks; to map the plurality of data blocks to a plurality of spatial streams by mapping the first symbol to a first data subcarrier in a first sub-band of a signal band in a first spatial stream of the plurality of spatial streams, and mapping the second symbol to a second data subcarrier in a second sub-band of the signal band in a second spatial stream of the plurality of spatial streams; and to transmit a Multi-In-Multi-Out (MIMO) transmission based on the plurality of spatial streams.