The cooling system for patients with fever is a mechanical, fluid-based system for cooling patients suffering from fever. The cooling system for patients with fever includes a reservoir for containing a cooling fluid, which is maintained at a desired temperature. A temperature sensor is received in the reservoir. The temperature sensor is immersed in the cooling fluid for measuring the temperature thereof. A chiller is also received in the reservoir for selectively cooling the cooling fluid when the temperature thereof, measured by the temperature sensor, is above a pre-set temperature threshold. The reservoir communicates with a cooling pad, which is formed from a padded layer having at least one channel embedded therein. At least one pump and tubing is provided for circulating the cooling fluid through the reservoir and the cooling pad. In use, the cooling pad is applied to the skin of a patient with a fever.