The present invention provides a method and apparatus for transmitting uplink control information (UCI) by user equipment in a wireless communication. The user equipment performs channel coding on information bits of the UCI to generate encoding information bits; performs modulation on the thus generated encoding information bits to generate complex modulation symbols; spreads the complex modulation symbols block-wise to a plurality of single carrier-frequency division multiple access (SC-FDMA) symbols based on an orthogonal sequence; and transmits the spread complex modulation symbols to a base station.