- 专利标题： BI-BENZYL ISOQUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF IN HEPATOPATHY TREATMENT AND PREVENTION
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申请号： US15504245申请日： 2015-06-29
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公开(公告)号： US20170260161A1公开(公告)日： 2017-09-14
- 发明人: Weidong Pan , Yibin Feng , Yazhou Liu , Ning Wang , Lan Huang , Guangyi Liang , Maosheng Zhang , Tianlei Li , Huayong Lou , Zhanxing Hu , Sheng Liu , Peixue Cao , Jinghua Ruan , Junjie Lan , Chao Chen
- 申请人： THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY , VERSITECH LTD.
- 优先权： CN201410403363.X 20140815
- 国际申请： PCT/CN2015/082626 WO 20150629
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D409/14 ; C07D405/14
摘要：
The invention disclosed a compound of general formula (I), a single stereoisomer thereof, a mixture of stereoisomers thereof, and a prodrug, pharmaceutically acceptable salt and metabolite thereof, X1, X2, X3, X4, R1, R2, x, y and z being as defined in the present invention.