- 专利标题： INHIBITORS OF IRAK4 ACTIVITY
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申请号： US15515383申请日： 2015-09-25
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公开(公告)号： US20170275297A1公开(公告)日： 2017-09-28
- 发明人: MICHAEL D. ALTMAN , BRIAN M. ANDRESEN , JASON D. BRUBAKER , MATTHEW L. CHILDERS , ANTHONY DONOFRIO , THIERRY FISCHMANN , CRAIG R. GIBEAU , SOLOMON D. KATTAR , CHARLES A. LESBURG , JONGWON LIM , JOHN K.F. MACLEAN , UMAR F. MANSOOR , ALAN B. NORTHRUP , JOHN M. SANDERS , LUIS TORRES
- 申请人： Michael D. ALTMAN , Brian M. ANDRESEN , Jason D. BRUBAKER , Matthew L. CHILDERS , Anthony DONOFRIO , Thierry FISCHMANN , Craig R. GIBEAU , Solomon D. KATTAR , Charles A. LESBURG , Jongwon LIM , John K.F. MACLEAN , Umar F. MANSOOR , Alan B. NORTHRUP , John SANDERS , Graham F. SMITH , Luis TORRES
- 申请人地址： US NJ RAHWAY
- 专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人地址： US NJ RAHWAY
- 国际申请： PCT/US15/52111 WO 20150925
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; A61K31/517 ; C07D403/04 ; C07D239/94 ; C07D401/04 ; A61K31/5377 ; C07D405/14 ; C07D401/14 ; C07D413/04 ; C07D405/04 ; C07D471/04 ; A61K31/5383 ; C07D491/048 ; C07D417/04 ; C07D409/04 ; A61K45/06
摘要：
The present invention relates to inhibitors of IRAK4 of Formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.
公开/授权文献
- US09969749B2 Inhibitors of IRAK4 activity 公开/授权日：2018-05-15