The invention relates to a machine for production of containers that are filled with a liquid product from preforms made from a thermoplastic material. The problem addressed by the invention is the proposing of such a machine which is easy to clean and disinfect. This problem is solved in that a machine comprises a heating section (1) for thermal conditioning of the preforms in a drying region (2) of the machine, a molding and filling section (3) for simultaneous molding and filling of the containers within a mold by a filled product inserted into the preforms under pressure in a wet region (4) of the machine and transport wheels (5, 6, 7, 8, 10) for transporting the preforms or the molded containers through the machine, wherein the distance of adjacent preforms is smaller in the heating section (1) than in the molding and filling section (3). The enlarging of the distances of the preforms between the heating section (1) and the molding and filling section (3) is performed by means of a transfer wheel (11) and the drying region (2) of the machine is separated from the wet region (4) of the machine by a lock (13) having a lock chamber (14). The machine is characterized in that the transfer wheel (11) for enlarging the distances of the preforms is arranged in whole or at least in part before the lock (13) in the drying region (2).