Invention Application
- Patent Title: BLOCK COPOLYMERS FOR THERAPEUTIC DRUG DELIVERY
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Application No.: US15145020Application Date: 2016-05-03
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Publication No.: US20170319704A1Publication Date: 2017-11-09
- Inventor: Willy Chin , Yukti Choudhury , Shujun Gao , James L. Hedrick , Xiyu Ke , Min-Han Tan , Jye Yng Teo , Yi Yan Yang
- Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Main IPC: A61K47/60
- IPC: A61K47/60 ; C08G63/42 ; A61K9/00 ; A61K47/58 ; C08G64/18 ; C08G64/02 ; C08G63/78 ; A61K31/704
Abstract:
Amphiphilic block copolymers (BCPs) were prepared comprising a poly(ethylene oxide) block and a biodegradable polycarbonate block functionalized with disulfide groups and carboxylic acid groups. The BCPs form self-assembled micellar particles in aqueous solution that can be loaded with hydrophobic drugs for therapeutic drug delivery. The loaded particles have small particle sizes (
Public/Granted literature
- US09901649B2 Block copolymers for therapeutic drug delivery Public/Granted day:2018-02-27
Information query
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