- 专利标题: FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREATMENT OF INFLAMMATION
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申请号: US15669410申请日: 2017-08-04
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公开(公告)号: US20170334920A1公开(公告)日: 2017-11-23
- 发明人: Antoni Krasinski , Sreenivas Punna , Solomon Ungashe , Qiang Wang , Yibin Zeng
- 申请人: ChemoCentryx, Inc.
- 申请人地址: US CA Mountain View
- 专利权人: ChemoCentryx, Inc.
- 当前专利权人: ChemoCentryx, Inc.
- 当前专利权人地址: US CA Mountain View
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D471/12 ; C07D471/04 ; C07D213/84 ; C07D213/81 ; C07D473/00 ; C07D213/79
摘要:
Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
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