An example method for facilitating remote memory access with memory mapped addressing among multiple compute nodes is executed at an input/output (IO) adapter in communication with the compute nodes over a Peripheral Component Interconnect Express (PCIE) bus, the method including: receiving a memory request from a first compute node to permit access by a second compute node to a local memory region of the first compute node; generating a remap window region in a memory element of the IO adapter, the remap window region corresponding to a base address register (BAR) of the second compute node; and configuring the remap window region to point to the local memory region of the first compute node, wherein access by the second compute node to the BAR corresponding with the remap window region results in direct access of the local memory region of the first compute node by the second compute node.