Invention Application
- Patent Title: GENOME-MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS
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Application No.: US15526952Application Date: 2015-11-21
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Publication No.: US20170356009A1Publication Date: 2017-12-14
- Inventor: Yuan Lu , Chen Ling , Arun Srivastava
- Applicant: University of Florida Research Foundation, Inc.
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Inc.
- Current Assignee: University of Florida Research Foundation, Inc.
- Current Assignee Address: US FL Gainesville
- International Application: PCT/US15/62037 WO 20151121
- Main IPC: C12N15/86
- IPC: C12N15/86
Abstract:
Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted terminal repeat (ITR) region. Exemplary modifications include ITR sequences comprising a glucocorticoid responsive element and/or a transcription factor binding site. Also provided are plasmids, libraries, rAAV particles, compositions, kits, and methods related to such vectors.
Public/Granted literature
- US10900053B2 Genome-modified recombinant adeno-associated virus vectors Public/Granted day:2021-01-26
Information query
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