发明申请
- 专利标题: TUMOR ANTIGEN PEPTIDE
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申请号: US15534315申请日: 2015-12-08
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公开(公告)号: US20170360911A1公开(公告)日: 2017-12-21
- 发明人: Noriyuki Sato , Toshihiko Torigoe , Yoshihiko Hirohashi , Takayuki Kanaseki , Sho Miyamoto , Vitaly Kochin , Masashi Goto
- 申请人: Sapporo Medical University , Sumitomo Dainippon Pharma Co., Ltd.
- 申请人地址: JP Sapporo-shi, Hokkaido JP Osaka-shi, Osaka
- 专利权人: Sapporo Medical University,Sumitomo Dainippon Pharma Co., Ltd.
- 当前专利权人: Sapporo Medical University,Sumitomo Dainippon Pharma Co., Ltd.
- 当前专利权人地址: JP Sapporo-shi, Hokkaido JP Osaka-shi, Osaka
- 优先权: JP2014-249169 20141209
- 国际申请: PCT/JP2015/084428 WO 20151208
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K7/06 ; G01N33/574 ; C07K16/30 ; C12N5/0783 ; G01N33/50 ; C12Q1/68 ; C07K16/28
摘要:
The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.
公开/授权文献
- US10765729B2 Tumor antigen peptide 公开/授权日:2020-09-08