利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.018 秒)

    TUMOR ANTIGEN PEPTIDE
    1.
    发明申请
    TUMOR ANTIGEN PEPTIDE 审中-公开

    公开(公告)号：US20170360911A1

    公开(公告)日：2017-12-21

    申请号：US15534315

    申请日：2015-12-08

    申请人： Sapporo Medical University ,  Sumitomo Dainippon Pharma Co., Ltd.

    发明人： Noriyuki Sato ,  Toshihiko Torigoe ,  Yoshihiko Hirohashi ,  Takayuki Kanaseki ,  Sho Miyamoto ,  Vitaly Kochin ,  Masashi Goto

    IPC分类号： A61K39/00 ,  C07K7/06 ,  G01N33/574 ,  C07K16/30 ,  C12N5/0783 ,  G01N33/50 ,  C12Q1/68 ,  C07K16/28

    摘要： The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.

    TUMOR ANTIGEN PEPTIDE
    2.
    发明申请
    TUMOR ANTIGEN PEPTIDE 审中-公开

    公开(公告)号：US20180147270A9

    公开(公告)日：2018-05-31

    申请号：US15534315

    申请日：2015-12-08

    申请人： Sapporo Medical University ,  Sumitomo Dainippon Pharma Co., Ltd.

    发明人： Noriyuki Sato ,  Toshihiko Torigoe ,  Yoshihiko Hirohashi ,  Takayuki Kanaseki ,  Sho Miyamoto ,  Vitaly Kochin ,  Masashi Goto

    IPC分类号： A61K39/00 ,  C12Q1/68 ,  C07K7/06 ,  C07K16/28 ,  C07K16/30 ,  C12N5/0783 ,  G01N33/50 ,  G01N33/574

    摘要： The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by YO-XO-ZO; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.

    TUMOR ANTIGEN PEPTIDE
    5.
    发明申请
    TUMOR ANTIGEN PEPTIDE 审中-公开

    公开(公告)号：US20190117751A1

    公开(公告)日：2019-04-25

    申请号：US16065488

    申请日：2016-12-27

    申请人： Sapporo Medical University

    发明人： Toshihiko Torigoe ,  Takayuki Kanaseki ,  Vitaly Kochin ,  Yasuhiro Kikuchi

    IPC分类号： A61K39/00 ,  A61K35/17 ,  C07K16/30 ,  A61P35/00 ,  A61K31/713 ,  C07K14/705 ,  C12N15/113 ,  C12N5/12 ,  G01N33/574 ,  A61K39/39

    摘要： The object of the present invention is to provide a detecting agent for specifically detecting a tumor cell, a tumor antigen peptide-specifically presented on a tumor cell, a pharmaceutical composition useful for the prevention and/or treatment of cancer, the pharmaceutical composition containing the tumor antigen peptide as an active ingredient, etc. The above object has been achieved by a tumor antigen peptide or its motif-substituted product, the tumor antigen peptide comprising 8 to 14 consecutive amino acids in an amino acid sequence of a protein encoded by a gene selected from the group consisting of PVT1, SUV39H2, ZNF724P, SNRNP40, and DYRK4, the tumor antigen peptide having an HLA binding ability.