发明申请
- 专利标题: CALIXPYRROLE COMPOUNDS AND CREATININE-SELECTIVE ELECTRODES COMPRISING THEM
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申请号: US15543151申请日: 2015-07-28
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公开(公告)号: US20170370948A1公开(公告)日: 2017-12-28
- 发明人: Louis ADRIAENSSENS , Pau BALLESTER , Francisco Javier ANDRADE , Pascal BLONDEAU , Francesc Xavier RIUS , Tomas De Aquino GUINOVART PAVON , Daniel HERNANDEZ ALONSO
- 申请人: FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ICIQ) , INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS , UNIVERSITAT ROVIRA I VIRGILI
- 申请人地址: ES Tarragona ES Barcelona ES Tarragona
- 专利权人: FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ICIQ) ,INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS,UNIVERSITAT ROVIRA I VIRGILI
- 当前专利权人: FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ICIQ) ,INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS,UNIVERSITAT ROVIRA I VIRGILI
- 当前专利权人地址: ES Tarragona ES Barcelona ES Tarragona
- 优先权: EP15382007.1 20150119
- 国际申请: PCT/EP2015/067241 WO 20150728
- 主分类号: G01N33/70
- IPC分类号: G01N33/70 ; C08K5/55 ; C08K5/5373 ; C07D491/22 ; B01J39/16 ; C08J5/22 ; C07F9/6571 ; G01N27/40 ; C08K5/32
摘要:
Compounds are of the formula (Ia), (Ib), (Ic), or are stereoisomers thereof, wherein: R1 is hydrogen, (C1-C20)alkyl; (C3-C20)alkenyl; (C3 C20)alkynyl; (C1-C6)alkyl-O—; (C3-C20)cycloalkyl; (C1 C20)haloalkyl; (C6-C20)aryl optionally substituted; (C6-C20)heteroaryl optionally substituted; R2 and R2′ are hydrogen; (C1-C20)alkyl; (C1-C6)alkyl-O—; (C1-C6)haloalkyl; halogen;cyano; and nitro; Z1 to Z4 are diradicals of formula (III) wherein Al and A2 are O—or —NR3-, wherein R3 is selected from the group consisting of hydrogen and (C1-C20)alkyl; and G is (C1-C6)alkyl; —P(═S)R5-; —P(═O)R4; P(═O)(OR4)-; —P(═O)(NR6R7)-; —S(=0)2-; S(═O)—; or —C(═O)—; and Y1 to Y4 are (C1-C8)alkyl; (C3-C7)cycloalkyl; (C6-C20)aryl optionally substituted; or (C6-C20)heteroaryl optionally substituted; and FG1 and FG2 are H, OH, or NHR8.
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