An ion implantation results in defects generated in a nitride semiconductor layer. If the nitride semiconductor layer is set at a particular temperature for a predetermined time period after the ion implantation, the defects may probably be clustering. Provided is a manufacturing method of a semiconductor device including a nitride semiconductor layer comprising: implanting impurities in the nitride semiconductor layer; and increasing a temperature of the nitride semiconductor layer from an initial temperature to a target temperature and annealing the nitride semiconductor layer at the target temperature for a predetermined time period; wherein in the annealing, in at least part of temperature regions below a first temperature between the initial temperature and the target temperature, the nitride semiconductor layer is annealed at a temperature increase speed lower than in a temperature region not lower than the first temperature.