- 专利标题： ANTI-CLL1 SPECIFIC SINGLE-CHAIN CHIMERIC ANTIGEN RECEPTORS (SCCARS) FOR CANCER IMMUNOTHERAPY
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申请号： US15546633申请日： 2016-01-25
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公开(公告)号： US20180009895A1公开(公告)日： 2018-01-11
- 发明人: Julianne SMITH , Julien VALTON , Philippe DUCHATEAU , Alexandre JUILLERAT , Arvind RAJPAL , Barbra Johnson SASU
- 申请人： Cellectis
- 优先权： DKPA201570044 20150126
- 国际申请： PCT/EP2016/051469 WO 20160125
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/00 ; C07K16/30 ; C07K14/725 ; C12N5/0783 ; C12N5/00
摘要：
The present invention relates to Chimeric Antigen Receptors (CAR) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward CLL1 positive cells. The engineered immune cells endowed with such CARs are particularly suited for immunotherapy for treating cancer, in particular leukemia.
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