Invention Application
- Patent Title: COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES
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Application No.: US15341117Application Date: 2016-11-02
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Publication No.: US20180016300A1Publication Date: 2018-01-18
- Inventor: On LEE , Mei-Hsuan TSAI
- Applicant: Industrial Technology Research Institute
- Applicant Address: TW Hsinchu
- Assignee: Industrial Technology Research Institute
- Current Assignee: Industrial Technology Research Institute
- Current Assignee Address: TW Hsinchu
- Main IPC: C07K7/02
- IPC: C07K7/02

Abstract:
A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), R1, R2 and R3 are each, independently, hydrogen, amino, nitro, halogen, hydroxyl, C1-C6 alkoxy, carboxylic acid, C1-C6 alkoxycarbonyl, C1-C6 amino, C1-C6 aminocarbonyl, C1-C6 alkyl, branched C1-C6 alkyl, C1-C6 cycloalkyl, C1-C6 heterocyclic, aryl or heteroaryl, provided at least one of R1 and R3 is an amino group. A linker-drug and a ligand-drug conjugate including the compound are also provided.
Public/Granted literature
- US10233212B2 Compounds, linker-drugs and ligand-drug conjugates Public/Granted day:2019-03-19
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