- 专利标题: Conjugates of Cell Binding Molecules with Cytotoxic Agents
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申请号: US14253881申请日: 2014-04-16
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公开(公告)号: US20180021448A9公开(公告)日: 2018-01-25
- 发明人: R. Yongxin Zhao , Yue Zhang , Yourang Ma
- 申请人: R. Yongxin Zhao , Yue Zhang , Yourang Ma , Hangzhou DAC Biotech Co., Ltd.
- 申请人地址: CN HANGZHOU
- 专利权人: Hangzhou DAC Biotech Co., Ltd.
- 当前专利权人: Hangzhou DAC Biotech Co., Ltd.
- 当前专利权人地址: CN HANGZHOU
- 主分类号: A61K45/06
- IPC分类号: A61K45/06
摘要:
A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a Formula (I), wherein T, L, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, and R13 are defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.
公开/授权文献
- US10399941B2 Conjugates of cell binding molecules with cytotoxic agents 公开/授权日:2019-09-03
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