A patient monitor (12) includes a display (14) and sensors (20, 22, 24) reading vital signs of a human subject. In a cardiovascular early warning scoring (cEWS) method, the human subject is classified using a plurality of cardiovascular deterioration classifiers (52, 152, 54, 56, 58) each trained respective to a different type of cardiovascular deterioration. The cardiovascular deterioration classifiers operate on a set of inputs characterizing the human subject including the at least one cardiovascular parameter (42) and the at least one respiratory parameter (44), such as tidal volume read by an airflow sensor (24). The cardiovascular early warning scores for the different types of cardiovascular deterioration are outputted on the display of the patient monitor. An empirical myocardial ischemia classifier (52) may be combined with at least one additional ischemia score generated by applying a set of rules (160) or a physiological model (162).