Technologies for providing network interface support for remote memory and storage failover protection include a compute node. The compute node includes a memory to store one or more protected resources and a network interface. The network interface is to receive, from a requestor node in communication with the compute node, a request to access one of the protected resources. The request identifies the protected resource by a memory address. Additionally, the network interface is to determine an identity of the requestor node and determine, as a function of the identity and permissions data associated with the memory address, whether the requestor node has permission to access the protected resource. Other embodiments are described and claimed.