A balloon system includes a balloon catheter extending from a proximal end portion to a distal end portion. The balloon catheter includes an inflation lumen therein. A balloon assembly is coupled with the distal end portion of the balloon catheter. The balloon assembly includes a balloon having distal and proximal balloon ends, has inflated and folded deflated configurations. One or more deflation guides are coupled with the balloon. The one or more deflation guides are configured to bias the balloon toward the folded deflated configuration.