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51 条记录 (耗时 0.018 秒)

    Two-part insertion tool and methods
    6.
    发明授权
    Two-part insertion tool and methods 有权

    公开(公告)号：US10806904B2

    公开(公告)日：2020-10-20

    申请号：US15467554

    申请日：2017-03-23

    申请人： Surmodics, Inc.

    发明人： Bruce M. Jelle ,  Joram Slager ,  Joseph Schmidt McGonigle ,  Nathan A. Lockwood

    IPC分类号： A61M25/06 ,  A61M25/00 ,  A61M39/06

    摘要： Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.

    Lubricious coatings with surface salt groups
    7.
    发明授权
    Lubricious coatings with surface salt groups 有权

    公开(公告)号：US10342898B2

    公开(公告)日：2019-07-09

    申请号：US15375442

    申请日：2016-12-12

    申请人： Surmodics, Inc.

    发明人： David E. Babcock ,  Joram Slager ,  Robert W. Hergenrother

    IPC分类号： B05D7/02 ,  B05D5/08 ,  B05D1/18 ,  A61L29/14 ,  A61L29/08 ,  B05D3/00 ,  B05D3/06 ,  B05D7/00

    摘要： Embodiments herein include coated medical devices and coatings with salt groups. In an embodiment, a coated medical device is included, the coated medical device including a substrate and a polymeric layer disposed over the substrate. The polymeric layer includes a polymer and has an exterior surface. The coated medical device further includes a plurality of salt groups bonded to the polymer of the polymeric layer and disposed on the exterior surface of the polymeric layer. The salt groups can be the reaction product of a reactive group with an acid or base. In an embodiment, a method of making a medical device is included. Other embodiments are also included herein.

    HEMODIALYSIS CATHETER SLEEVE
    9.
    发明申请
    HEMODIALYSIS CATHETER SLEEVE 审中-公开
    HEMODIALYSIS导管套管

    公开(公告)号：US20170072129A1

    公开(公告)日：2017-03-16

    申请号：US15257252

    申请日：2016-09-06

    申请人： Surmodics, Inc.

    发明人： Joram Slager ,  Joe McGonigle ,  Anh Tri La ,  David E. Babcock ,  Bruce Jelle ,  Aleksey Kurdyumov ,  Timothy M. Kloke ,  Charlie Olson ,  Gary Maharaj ,  Nathan Lockwood

    IPC分类号： A61M1/36 ,  A61M39/02 ,  A61M25/10

    摘要： A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.

    摘要翻译： 血液透析血管通路装置包括尺寸和形状可密封地连接到血液透析导管的近端，耦合到近端的可移动结构，联接到可移动区域的尺寸和形状用于固定在患者身上的细长套筒 耦合到所述固定结构，并且其尺寸和形状用于插入到患者的脉管系统中，以及在所述内腔的远端处的阀。 当血液透析导管插入装置并且联接到近端时，近端相对于固定结构的远端运动通过穿过装置的阀将细胞套筒内的位置偏离血液透析导管的远端， 进入病人的血液。

    Hydrophobic active agent particle coatings and methods for treatment
    10.
    发明授权
    Hydrophobic active agent particle coatings and methods for treatment 有权

    公开(公告)号：US11123459B2

    公开(公告)日：2021-09-21

    申请号：US15842110

    申请日：2017-12-14

    申请人： Surmodics, Inc.

    发明人： Joram Slager ,  Rick Murphy

    IPC分类号： A61L29/16 ,  A61L29/08 ,  C08L39/06 ,  C08L67/04 ,  A61M25/10

    摘要： Drug delivery coatings and devices including the same are described herein. The drug delivery coating has a first coated layer with non-ionic polymer and photogroups, a second coated layer with acid polymer in contact and hydrogen bonded with the first layer, particles with hydrophobic therapeutic agent, and cationic agent. The coating can be provided on a balloon catheter, and the particles and cationic agent can be transferred to tissue during a medical procedure, such as an angioplasty procedure, for a therapeutic effect.