发明申请
- 专利标题： CYCLIC COMPOUND
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申请号： US15572231申请日： 2016-05-06
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公开(公告)号： US20180118708A1公开(公告)日： 2018-05-03
- 发明人: Toshitake KOBAYASHI , Morihisa SAITOH , Yasufumi WADA , Hiroshi NARA , Nobuyuki NEGORO , Masashi YAMASAKI , Takahiro TANAKA , Naomi KITAMOTO
- 申请人： Takeda Pharmaceutical Company Limited
- 申请人地址： JP Chuo-ku, Osaka-shi, Osaka
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Chuo-ku, Osaka-shi, Osaka
- 优先权： JP2015-095818 20150508
- 国际申请： PCT/JP2016/063628 WO 20160506
- 主分类号： C07D317/72
- IPC分类号： C07D317/72 ; A61P37/00 ; A61P29/00 ; A61P25/02 ; A61P1/16 ; A61P9/10
摘要：
The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of autoimmune disease and/or inflammatory disease or diseases such as chemotherapy-induced peripheral neuropathy (CIPN), chemotherapy-induced neuropathic pain (CINP), liver injury, ischemia-reperfusion injury (IRI) and the like.The present invention relates to a compound represented by formula (I) and a salt thereof: (wherein, each symbol is explained in greater detail in the specification).