发明申请
- 专利标题： QUINOLINONE PYRIMIDINES COMPOSITIONS AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS
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申请号： US15712446申请日： 2017-09-22
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公开(公告)号： US20180134682A1公开(公告)日： 2018-05-17
- 发明人: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, Jr. , Justin Andrew Caravella , Wei Lu
- 申请人： FORMA Therapeutics, Inc.
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D405/14 ; C07D401/14 ; C07D403/12 ; C07D471/04 ; C07D409/14 ; C07D413/14 ; C07D417/14
摘要：
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, B, W1, W2, W3, and R1-R6 are described herein.
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