The various embodiments described herein include methods, devices, and systems for customizing dental care. In one aspect, an oral care agent dispenser device includes: (1) multiple chambers each configured to receive a cartridge containing a different oral care agent ingredient of a plurality of oral care agent ingredients; (2) memory configured to store an oral care agent formulation that includes one or more of the plurality of oral care agent ingredients; and (3) a dispenser positioned above an oral care agent dispensing region, the dispenser configured to dispense one or more of the plurality of oral care agent ingredients in accordance with the oral care agent formulation.