- 专利标题： PEPMIXES TO GENERATE MULTIVIRAL CTLS WITH BROAD SPECIFICITY
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申请号： US15905176申请日： 2018-02-26
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公开(公告)号： US20180187152A1公开(公告)日： 2018-07-05
- 发明人: Ann Marie Leen , Juan Fernando Vera Valdes , Cliona M. Rooney , Ulrike Gerdemann
- 申请人： Baylor College of Medicine
- 主分类号： C12N5/0783
- IPC分类号： C12N5/0783 ; C12N7/00 ; A61K39/12 ; A61K39/00
摘要：
The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.
公开/授权文献
- US11118164B2 Pepmixes to generate multiviral CTLs with broad specificity 公开/授权日：2021-09-14
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