Invention Application
- Patent Title: NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND OTHER CANCERS
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Application No.: US15918788Application Date: 2018-03-12
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Publication No.: US20180207253A1Publication Date: 2018-07-26
- Inventor: Toni WEINSCHENK , Andrea MAHR , Jens FRITSCHE , Phillip MUELLER , Anita WIEBE , Sara KUTSCHER
- Applicant: IMMATICS BIOTECHNOLOGIES GMBH
- Priority: GB1423016.3 20141223; GB1501017.6 20150121
- Main IPC: A61K39/00
- IPC: A61K39/00 ; G01N33/68 ; C07K14/725 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; A61K35/17 ; C12N15/115 ; C12N5/0783 ; C07K16/18 ; C07K14/74 ; A61K35/12

Abstract:
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVYDGEEHSV (SEQ ID NO: 303), in which the peptide is in a complex with an MHC molecule.
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